Urology Annals

: 2014  |  Volume : 6  |  Issue : 3  |  Page : 244--246

Simple cyst of urinary bladder

Yang Bo 
 Department of Urology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, 116027, China

Correspondence Address:
Yang Bo
Shahekou District, ZhongShan Road, 467, Dalian, Liaoning Province, 116 027


Simple cysts are rare in the urinary bladder and can pose a diagnostic dilemma to both the urologist and the histopathologist. No case study was found in the database of Elsevier Science Direct, Spring-Link, or PubMed. We present two cases of subserous cyst in the bladder and discuss the diagnosis and treatment of the condition. The cystic lesion at bladder dome was detected by radiologic examination and confirmed by cystoscopy. In case 1, transurethral resection was first performed which was followed by partial cystectomy; In case 2, the cyst was removed with the urachus using laparoscopic surgery. The patients recovered uneventfully and the histopathology showed cysts in subserous layer of urinary bladder. The bladder cyst should be distinguished from urachal tumor, and laparoscopic partial cystectomy is the preferred operative procedure.

How to cite this article:
Bo Y. Simple cyst of urinary bladder.Urol Ann 2014;6:244-246

How to cite this URL:
Bo Y. Simple cyst of urinary bladder. Urol Ann [serial online] 2014 [cited 2022 Jan 24 ];6:244-246
Available from: https://www.urologyannals.com/text.asp?2014/6/3/244/134288

Full Text


Urinary bladder is a cystic formed organ that consists of stratum mucosum, lamina muscularis, and serous membrane. Most of the tumors in the urinary bladder are of epithelial origin and various cyst-like lesions can occur intra- or extravesically; very few of them are derived from the bladder wall. Here we present two cases of simple subserous cyst of bladder which were removed via partial cystectomy.


0Case 1

A 55-year-old woman presented with a 4-month history of frequency, urgency, and vague abdominal pain in right lower quadrant. There was no hematuria, dysuria or fever. Abdominal and genital examination results were normal except for slight tenderness in right suprapubic region. Urinalysis result was normal. Urinary tract Doppler sonography revealed a thin-walled 3.7 cm × 3.1 cm × 2.7 cm cystic structure (a sharp interface towards the bladder cavity; absence of internal echoes and signal of blood flow) arising from the right side of the bladder, adjacent to the dome. Computerized tomography (CT) scan [Figure 1]a showed a local protrusion of the right anterior bladder wall and a faint septum-like structure in the right side of the urinary bladder lumen, which was detected by intravenous urography (IVU) as a filling defect outside the right ureteral orifice [Figure 1]b. There was no hydronephrosis or ureteral dilation.

Cystoscopy revealed an oval cystic lesion measuring 4 × 3 × 2.5 cm in the right side of the bladder dome, which had a smooth surface with the appearance of vesical mucosa [Figure 1]c. Transurethral resection was performed first to remove the tectum of the cyst. Some luculent and colorless fluid inside and a single septation were revealed [Figure 1]d. The intravesical part of the cyst wall was thicker than the contralateral wall, lacking of muscular tissue on macroscopic observation.{Figure 1}

Given that a post-operative diverticulum in situ could develop, a partial cystectomy was immediately performed [Figure 1]e. Histopathology [Figure 1]f showed a cyst in subserous layer of urinary bladder. The cyst wall was composed of thin fibrous connective tissue and lined with flat monostratum/cubical epithelium in the inner side.

Case 2

A 43-year-old woman suffered from intermittent lower abdominal pain with slight urinary frequency and urgency for three years. Physical examination and urinalysis showed normal results. Ultrasonography revealed a cyst measuring 2.4 × 1.2 cm at the mid-anterior bladder wall. CT scan showed a small (1.8 cm in diameter) well-defined cystic mass with low density of 17HU and no enhancement at the dome of the bladder [Figure 2]a. Cystoscopy revealed a cyst-like mass with smooth surface at the anterior wall of the urinary bladder. The cyst measured 2.0 × 1.8 cm and decreased in size with the inflating of the bladder [Figure 2]b. Laparoscopic partial cystectomy was performed approximately 1 cm away from the outer margin of the lesion under cystoscopic guidance [Figure 2]c. Meanwhile the urachus was removed. Pathological examination [Figure 2]d revealed capsule-like tissue in bladder wall with chronic inflammation and uroepithelium proliferation.{Figure 2}

The post-operative course of both patients was uneventful, and at 11 and 4 months respectively, the patients remain free of recurrence.


According to histological classification of urinary bladder tumors formulated by WHO in 1973, cysts in bladder are regarded as tumor-like lesions; however, only two types of cyst were identified. Urachal cysts are typically in the dome and anterior wall, whereas cloacal cysts are confined to the posterior wall. A lot of other cystic lesions such as dermoid cyst, mόllerian duct cyst, seminal vesicale cyst, ureterocele and hydatid cyst are derived from the bladder wall exogenously or endogenously. These abnormalities, rare or not, always present the typical clinical feature, distinctive histopathological change and in characteristic predisposing areas. The cases in our report seemed to lack specific clinical manifestation, and the etiology was unclear. Although ultrasound can identify a cystic lesion, it is necessary to perform CT scan before surgery unless we have good experience in making differential diagnosis. The preoperative diagnosis was built by radiological examination. Usually bladder tumors may be recognized as pedunculated, radiolucent filling defects projecting into the lumen. In our cases, the CT scan showed cyst like lesion but not solid mass, this is the main evidence for ruling out a malignant disease. However, it was confirmed by cystoscopy. The post-operative histological examination showed a simple cyst of bladder wall, which was different from all the above-mentioned cystic lesions.

Elsevier Science Direct, Spring-Link and PubMed were searched using the key words of urinary bladder, vesicle, cystis, cyst (s), cystic lesion, hydatoncus and hygroma, but no similar case was found. So we presumed that bladder cyst or namely subserous cyst of urinary bladder should be identified as a special type of tumor-like lesion of bladder because of its unknown etiology. In our experience the bladder cyst is easy to be distinguished from other bladder cystic lesions except for some urachal abnormality. Diagnostic evaluation of suspected urachal disorders include intravenous pyelography, cystography, sinography, cystoscopy, US and CT. [1],[2] A midline cystic lesion extending from the umbilicus to the dome of the bladder on US and CT is suggestive of urachal abnormalities. Nimmonrat A et al., thought that the urachal cyst appears echogenic on ultrasound (US) and enhancement on CT because of superimposed infection. [2]

In our opinion, for those without clinical manifestation and complication, watchful waiting is recommended because of the benign biologic behavior. If the surgical procedure is considered, partial cystectomy is better than transurethral resection of the cyst because the former prevents the formation of diverticulum or pseudo urinary cyst. Laparoscopic partial cystectomy (LPC) performed by the transperitoneal approach is a safe and effective method. [3] Generally the lesion is not readily apparent from laparoscopic views, and intraoperative cystoscopy can be used to identify the exact location of the cyst from outside the bladder. [4]


Subserous cyst of urinary bladder is rare and should be distinguished from urachal tumor. Laparoscopic partial cystectomy is the preferred operative procedure.


1Yu JS, Kim KW, Lee HJ, Lee YJ, Yoon CS, Kim MJ. Urachal remnant diseases: Spectrum of CT and US findings. Radiographics 2001;21:451-61.
2Nimmonrat A, Na-ChiangMai W, Muttarak M. Urachal abnormalities: Clinical and imaging features J. Singapore Med J 2008;49:930-5.
3Tai HC, Chung SD, Wang SM, Chueh SC, Yu HJ. Laparoscopic partial cystectomy for various bladder pathologies. BJU Int 2007;100:382-5.
4Colombo JR Jr, Desai M, Canes D, Frota R, Haber GP, Moinzadeh A, et al. Laparoscopic partial cystectomy for urachal and bladder cancer. Clinics (Sao Paulo) 2008;63:731-4.